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Research Studies Completed
Hunger & Food Addiction
- Changing Perceptions of Hunger On a High Nutrient Density Diet.
Joel Fuhrman, M.D., Barbara J. Sarter, Ph.D., Steve Acocella. Nutrition Journal. November 2010, 9:51
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Hunger and Food Addiction: The Changing Perception of Hunger on a High Nutrient Density Diet
This study arose from our clinical observations that a diet high in micronutrients decreases food cravings and overeating behaviors. We hypothesize that a diet low in micronutrients leads to a build-up of toxic metabolites and increased oxidative stress that can create physical symptoms of withdraw in between meals. These symptoms such as weakness, fatigue, headaches, irritability and tremors are commonly interpreted as hunger. We believe that these symptoms are secondary to “toxic hunger” which arises from a micronutrient-poor diet.
The study is a retrospective analysis of 700 participants from Dr. Fuhrman's website. Survey questions were administered and referred to two classifications of diet: The Standard American Diet (SAD) and the High Nutrient Density Diet (HNDD). The purpose of the analysis was to compare the differences in the experience of hunger in the HND diet versus the SAD diet.
This study demonstrated that individuals who adopted a HND diet did not experience uncomfortable sensations of hunger after several weeks on the HND diet. But, more importantly, in the majority of participants, the symptoms commonly considered hunger by traditional views, disappeared and were replaced by signals of what the researchers consider “true hunger” felt in the throat area. This transitioning of hunger symptoms was integral to successful weight loss and long-term maintenance of a normal weight.
- Dunaief D, Gui-shuang Y, Fuhrman J, et al. Glycemic and cardiovascular parameters improved in type 2 diabetes with the high nutrient density diet. Presented at the 5th IANA (International Academy on Nutrition and Aging) meeting July 26 & 27, 2010 Hyatt Regency Tamaya Resort & Spa 1300 Tuyuna Trail Santa Ana Pueblo, NM, USA J Nutr Health Aging 2010;14:500.
Diabetes: Improved Glycemic and Cardiovascular Parameters in Type 2 Diabetic Patients on a High Nutrient Density Diet.
This is a retrospective case series, looking at the potential efficacy of the HND (high nutrient dense) diet for participants who are compliant. Though further study is needed, the results were encouraging: 62% of the participants became non-diabetic (HbA1C of less than 6.0%), a mean decrease in HbA1C of 2.35% and a reduction in the mean number of drugs used from 4 to1.
Exercise & Nutrition
- Fueling the Vegetarian (Vegan) Athlete.
Joel Fuhrman, M.D., Deana Ferreri Ph.D. American College of Sports Medicine July/August 2010 issue of Current Sports Medicine Reports.
In this article, we review the state of the literature on vegetarian diets and athletic performance, discuss prevention of potential micronutrient deficiencies that may occur in the vegan athlete and provide strategies on meeting the enhanced caloric and protein needs of an athlete with a plant-based diet.
Effect of a High Nutrient Density Diet On Long-Term Weight Loss: A Retrospective Chart Review.
Barbara Sarter, PhD; Joel Fuhrman, MD Alternative Therapies 2008; 14(3):48-53.
This study reported sustained and highly effective reductions in weight and cardiac risk factors in a cohort of patients treated in a private family practice office with a high nutrient vegetable based diet emphasizing a liberal intake of fresh vegetables, fruits, beans and nuts.
- Effects of a Very-High-Fiber Vegetable, Fruit, and Nut Diet on Serum Lipids and Colonic Function.
Jenkins DJ; Kendall CW; Popovich DG et al. Metabolism 2001; 50 (4): 494-503.
This study tested the effects of a HND diet style in 30 healthy volunteers. The volunteers were divided equally into three groups comparing those adopting a HND diet style with those adopting a starch-based diet or a low fat diet. With the nutritarian type diet, LDL cholesterol was reduced by 33 % (+/- 4%, P<.001) within a few weeks.
- Brief Case Reports of Medically Supervised, Water-Only Fasting Associated With Remission of Autoimmune Disease.
Joel Fuhrman, MD, Barbara Sarter, PHD, RN, FNP, and David J. Calabro, DC. Alternative Therapies 2001:8(4):1-3.
Six cases reported in which medically supervised, water-only fasting followed by a vegan diet resulted in reduction in pain and inflammation markers in patients with autoimmune illnesses.
- Medically Supervised Water-Only Fasting in the Treatment of Hypertension.
Goldhamer A, Lisle D, Anderson SV, Campbell TC. Journal of Manipulative and Physiological Therapeutics. 2001; 25 (5): 335-339.
- Medically Supervised Water-Only Fasting in the Treatment of Borderline Hypertension.
Goldhamer AC, Lisle DJ, Sultana P, Anderson SV, Parpia B, Hughes B, Campbell TC. The Journal of Alternative and Complementary Medicine 2002; 8 (5): 643-650.